Volume 4 | Issue 2 | 2023

Editorial

“Beyond the Bedside: A Comprehensive Look at ICU Admission and Discharge Criteria” and Illuminating the Crucial Role of the Intensivist in ICU Management
[Swapnaja P. Shelke, Shweta Deshmukh, Khalid Khatib]

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Case Reports

A Case of Reactivation of Acute Rheumatic Fever in a Known Case of Rheumatic Valvular Heart Disease
[Jay Malviya, Pranoti More, Yogesh Rasal]

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Acute rheumatic fever (ARF) is an inflammatory disease that can develop as a complication of untreated or inadequately treated streptococcal throat infection, specifically caused by group A Streptococcus bacteria (Streptococcus pyogenes). Diagnosis of ARF is based on the Jones Criteria, which include major and minor criteria related to clinical presentation, laboratory findings (such as elevated anti-streptolysin O titer), and evidence of preceding streptococcal infection.
Key words: Acute rheumatic fever, rheumatic valvular heart disease, Jones criteria
A Rare Case of Unilateral Ovarian Sex Cord Tumor with Annular Tubules
[Siddhi Gaurish Sinai Khandeparkar, Maithili Kulkarni, Vaishali R. Aphale, Bageshri P. Gogate, Sheetal Gosavi, Ketki Ghanekar]


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Sex cord tumor with annular tubules (SCTATs) is a rare ovarian tumor accounting for <1% of sex cord stromal tumors. It is of two types sporadic and syndromic. Syndromic SCTATs are regarded as benign, are usually bilateral, and are associated with germline STK11 mutations on chromosome 19p13.3 characteristic of Peutz–Jeghers syndrome. Sporadic SCTAT cases are unilateral and about 20% of them are regarded to manifest extra ovarian spread. Here, we intend to put on record a rare case of sex cord stromal tumor with annular tubules in a 49-year female presenting with left adnexal mass.
Key words: Ovarian tumor, hyperestrinism, sex cord tumor with annular tubules, inhibin
A Case of Pancytopenia in a Young Female
[Anandita Gulhane, Siddhant Ingle, Shubham Gaonkar, Nitin Suryawanshi]


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Aplastic anemia (AA) is a rare but serious hematologic disorder associated with hematopoietic failure that results due to the decrease or absence of hematopoietic precursor cells in the bone marrow. AA has equal distribution between race and gender, and can occur at any age. Patients usually present with generalized, non-specific complaints, and treatment depends on age, disease severity, donor availability, and clinical and laboratory presentation. Here, we report the case of a 21-year-old woman who presented to the emergency department with vague symptoms of dyspnea, fatigue, pedal edema, and fever, and on further evaluation, a laboratory panel revealed persistent pancytopenia with hypocellular bone marrow and an excellent response to immunosuppressive therapy.
Key words: Pancytopenia, Aplastic Anaemia, Bone Marrow, Hypocellular

A Case of Acyclovir-induced Encephalopathy in a Chronic Kidney Disease Patient
[Abhijit Pundkar, Saurabh Padole, Vishal Dhas, Swapnaja Shelke, Shweta Deshmukh, Jitendra Ingole]

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Acyclovir (ACV)-associated encephalopathy is a very rare entity induced by ACV and valacyclovir, a prodrug of ACV. Clinically differentiating herpes zoster encephalopathy from ACV-induced encephalopathy is very challenging. Zoster encephalopathy should improve with ACV, whereas drug-induced neurotoxicity will get worse if the medication is continued. Manifestations of ACV neurotoxicity include altered consciousness, tremor, myoclonus, and dysarthria. However, headache, fever, convulsions, and focal symptoms are rare.
Key words: Acyclovir, Encephalopathy, Herpes zoster.
A Case of Drug-induced Hypokalemic Paralysis
[Pranav Shelke, V. Rathi, P. Lalge, S. Deshmukh, S. Shelke, J. Ingole]


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Hypokalemic paralysis is a rare condition marked by sudden muscle weakness due to low potassium levels. . Prompt recognition and potassium supplementation led to symptom resolution, emphasizing the importance of early intervention in managing this potentially life-threatening condition.

Key words: Potassium, Hypokalemia , Paralysis

Acroangiodermatitis of Mali: A Rare Case Report
[Pallavi More, Chinmay Ratkanthiwar, Swati Shandilya, Swapna Sheth, Nitin Chaudhari]


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Acroangiodermatitis of Mali also known as pseudo-Kaposi sarcoma is an unusual, benign condition. It is clinically presents as purple-colored patches, which can be plaques or nodules. It is located mostly on the extensor surface of lower extremities and seen most commonly in patients with chronic venous insufficiency and arteriovenous malformation. It looks like aggressive conditions like Kaposi’s sarcoma. Hence, histopathological examination is required for its diagnosis. Herein, we report a patient who presented with a chronic history of purple-colored papules and plaques over both legs which was later histopathologically confirmed to be case of acroangiodermatitis of Mali.
Key words: Acroangiodermatitis of mali, Arteriovenous malformation, Venous insufficiency
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